Three-Dimensional Cardiac Electrical Activity Simulation on Cluster and Grid Platforms

• Published in: High Performance Computing for Computational Science - VECPAR 2004 pp. 219 - 232
• Main Authors: Alonso, J. M., Ferrero, J. M., Hernández, V., Moltó, G., Monserrat, M., Saiz, J.
• Format: Book Chapter Conference Proceeding
• Language: English
• Published: Berlin, Heidelberg Springer Berlin Heidelberg 2005; Springer
• Series: Lecture Notes in Computer Science
• Subjects: Action Potential Propagation; Applied sciences; Computer science; control theory; systems; Computer systems and distributed systems. User interface; Conjugate Gradient Method; Exact sciences and technology; Globus Toolkit; Grid Infrastructure; Parallel Execution; Software; Productivity; High performance; Parallel algorithm; Electrical activity; Grid; Action potential; Distributed system; Distributed computing; Modeling; Tissue; Three dimensional model; Electrical simulation; Simulator
• ISBN: 9783540254249; 3540254242
• ISSN: 0302-9743; 1611-3349
• DOI: 10.1007/11403937_18

Simulation of action potential propagation on cardiac tissues represents both a computational and memory intensive task. The use of detailed ionic cellular models, combined with its application into three-dimensional geometries turn simulation into a problem only affordable, in reasonable time, with High Performance Computing techniques. This paper presents a complete and efficient parallel system for the simulation of the action potential propagation on a three-dimensional parallelepiped modelization of a ventricular cardiac tissue. This simulator has been integrated into a Grid Computing system, what allows an increase of productivity in cardiac case studies by performing multiple concurrent parallel executions on distributed computational resources of a Grid.