MR imaging of Vogt-Koyanagi-Harada syndrome with leptomeningeal enhancement

We describe a 28-year-old man with presumed VKH syndrome, whose presenting symptoms were bilateral impaired vision and headaches. Orbital MR imaging findings included bilateral choroidal and retrobulbar contrast enhancement, while brain findings included white matter abnormalities on FLAIR and lepto...

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Bibliographic Details
Published inAmerican journal of neuroradiology : AJNR Vol. 32; no. 9; pp. E169 - E171
Main Authors Lohman, B D, Gustafson, C A, McKinney, A M, Sarikaya, B, Silbert, S C
Format Journal Article
LanguageEnglish
Published United States American Society of Neuroradiology 01.10.2011
Subjects
Adult
Brain - pathology
Case Reports
Early Diagnosis
Humans
Magnetic Resonance Imaging - methods
Male
Meninges - pathology
Meningitis, Aseptic - pathology
Uveomeningoencephalitic Syndrome - pathology
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Summary:We describe a 28-year-old man with presumed VKH syndrome, whose presenting symptoms were bilateral impaired vision and headaches. Orbital MR imaging findings included bilateral choroidal and retrobulbar contrast enhancement, while brain findings included white matter abnormalities on FLAIR and leptomeningeal enhancement. Pachymeningeal enhancement has been described previously; herein, we report a patient with VKH syndrome presenting solely with leptomeningeal enhancement. Thus, MR imaging may detect early CNS involvement by VKH disease before the onset of neurologic symptoms.
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ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.A2279