Acute coronary syndrome in the oncology patient: An avoidable event?

5-Fluorouracil is a first-line agent in several cancer-therapy regimens. Cardiotoxicity is common, with coronary artery disease being an important risk factor. We report the case of an acute coronary syndrome presumably induced by 5-FU, in a patient with previously unknown and asymptomatic coronary...

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Published inRevista portuguesa de cardiologia Vol. 37; no. 9; p. 791.e1
Main Authors Félix-Oliveira, Afonso, Vale, Nélson, Madeira, Sérgio, Mendes, Miguel
Format Journal Article
LanguageEnglish
Portuguese
Published Portugal 01.09.2018
Subjects
Cardiotoxicidade
5‐FU
Cardiotoxicity
Angina Pectoris
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Abstract 5-Fluorouracil is a first-line agent in several cancer-therapy regimens. Cardiotoxicity is common, with coronary artery disease being an important risk factor. We report the case of an acute coronary syndrome presumably induced by 5-FU, in a patient with previously unknown and asymptomatic coronary artery disease, with an estimated intermediate risk for cardiovascular events. Pre-chemotherapy risk evaluation and optimal patient care are still not standardized in this clinical scenario.
AbstractList 5-Fluorouracil is a first-line agent in several cancer-therapy regimens. Cardiotoxicity is common, with coronary artery disease being an important risk factor. We report the case of an acute coronary syndrome presumably induced by 5-FU, in a patient with previously unknown and asymptomatic coronary artery disease, with an estimated intermediate risk for cardiovascular events. Pre-chemotherapy risk evaluation and optimal patient care are still not standardized in this clinical scenario.
Author Mendes, Miguel
Félix-Oliveira, Afonso
Madeira, Sérgio
Vale, Nélson
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  organization: Serviço de Cardiologia, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal; Faculdade de Medicina da Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisboa, Portugal. Electronic address: afonso.felix.oliveira@gmail.com
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  organization: Serviço de Cardiologia, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal; Nova Medical School, Universidade Nova de Lisboa, Lisboa, Portugal
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Keywords Cardiotoxicidade
5‐FU
Cardiotoxicity
Angina Pectoris
Language English
Portuguese
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