Acute coronary syndrome in the oncology patient: An avoidable event?

5-Fluorouracil is a first-line agent in several cancer-therapy regimens. Cardiotoxicity is common, with coronary artery disease being an important risk factor. We report the case of an acute coronary syndrome presumably induced by 5-FU, in a patient with previously unknown and asymptomatic coronary...

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Bibliographic Details
Published inRevista portuguesa de cardiologia Vol. 37; no. 9; p. 791.e1
Main Authors Félix-Oliveira, Afonso, Vale, Nélson, Madeira, Sérgio, Mendes, Miguel
Format Journal Article
LanguageEnglish
Portuguese
Published Portugal 01.09.2018
Subjects
Cardiotoxicidade
5‐FU
Cardiotoxicity
Angina Pectoris
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Summary:5-Fluorouracil is a first-line agent in several cancer-therapy regimens. Cardiotoxicity is common, with coronary artery disease being an important risk factor. We report the case of an acute coronary syndrome presumably induced by 5-FU, in a patient with previously unknown and asymptomatic coronary artery disease, with an estimated intermediate risk for cardiovascular events. Pre-chemotherapy risk evaluation and optimal patient care are still not standardized in this clinical scenario.
ISSN:2174-2030
DOI:10.1016/j.repc.2017.04.010