Impact of asymptomatic maternal SARS-CoV-2 infection on foetal growth

• Published in: Clínica e investigación en ginecología y obstetricia Vol. 49; no. 3; p. 100756
• Main Authors: Bonmatí-Santané, A, Maroto, A, Martínez-Diago, C, Perez-Del-Campo, D, Pérez-de-Puig, M, Mira-Andrés, M, Álvarez-Castaño, E
• Format: Journal Article
• Language: English; Spanish
• Published: Spain 01.07.2022
• Subjects: COVID-19; SARS-CoV-2; Foetal growth restriction; Prenatal diagnosis; Maternal infection
• ISSN: 0210-573X
• DOI: 10.1016/j.gine.2022.100756

The impact of asymptomatic infection by SARs-CoV-2 on foetal growth has not been described. The purpose of our study is to determine whether there is an increased risk of foetal growth restriction in pregnancies in which asymptomatic or mild infection by SARS-CoV-2 has been detected. Retrospective case-control study with a subset of pregnant women with a small for gestational age foetus. Groups were established according to birth weight percentile. Previous SARS-CoV-2 infection was defined by positive antibodies obtained on admission to hospital for delivery. No statistically significant differences between controls and cases were recorded in terms of positive IgG antibodies (11.5 vs. 8.8%). There were no premature births or significant differences in the date or type of delivery. Asymptomatic infection by SARs-CoV-2 during pregnancy does not seem to affect foetal growth.