Clinical features and evolution of organ dysfunctions in sepsis

In sepsis, the systemic inflammatory response is adapted to the etiologic agent and the increase in the level of mediators is associated with organ dysfunction. Currently, a rapid assessment of patient ability to develop an adequate immune response is not possible, the response mechanisms being simi...

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Bibliographic Details
Published inRevista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi Vol. 118; no. 1; p. 71
Main Authors Bejan, Codrina, Loghin, Isabela, Roşu, F, Dorobăţ, G, Dorobăţ, Carmen-Mihaela
Format Journal Article
LanguageEnglish
Published Romania 01.01.2014
Subjects
Adolescent
Adult
Aged
Aged, 80 and over
Bacteremia - complications
Bacteremia - diagnosis
Bacteremia - mortality
Child
Child, Preschool
Female
Hospital Mortality
Humans
Male
Middle Aged
Multiple Organ Failure - diagnosis
Multiple Organ Failure - microbiology
Multiple Organ Failure - mortality
Prognosis
Retrospective Studies
Severity of Illness Index
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Summary:In sepsis, the systemic inflammatory response is adapted to the etiologic agent and the increase in the level of mediators is associated with organ dysfunction. Currently, a rapid assessment of patient ability to develop an adequate immune response is not possible, the response mechanisms being similar in the context of different etiological agents. To find statistical arguments for the evolution of laboratory parameters in sepsis patients. This retrospective study included 90 patients diagnosed with sepsis. The clinical, etiological, and laboratory data, and Carmeli and APACHE II prognostic scores were analyzed. The data were processed using SPSS version 16.0. The causative agents was identified in 16 cases; organ involvement and systemic response varied, and no statistical correlations were found between the inflammatory syndrome parameters and Carmeli or APACHE II prognostic scores or identification of the causative agent. Statistical correlations were found between maximum blood glucose levels and the presence of organ dysfunction in the studied sepsis patients. No correlations were found between sepsis severity and the presence of anemia or thrombocytopenia, or between fever syndrome and inflammatory syndrome.
ISSN:0048-7848