The protective effects of hesperidin pretreatment on kidney and remote organs against renal ischemia-reperfusion injury

• Published in: European review for medical and pharmacological sciences Vol. 27; no. 7; p. 2808
• Main Authors: Karacaer, C, Erdogan, D G, Tanyeli, A, Baylan, H, Eraslan, E, Guler, M C, Polat, E, Comakli, S
• Format: Journal Article
• Language: English
• Published: Italy 01.04.2023
• Subjects: Animals; Antioxidants - pharmacology; Hesperidin - pharmacology; Hesperidin - therapeutic use; Ischemia; Kidney; Oxidative Stress; Rats; Reperfusion Injury - drug therapy; Reperfusion Injury - prevention & control

As an antioxidant and anti-inflammatory agent, Hesperidin was investigated to prove whether it prevents damage to the kidney and lung tissues of rats undergoing renal ischemia-reperfusion injury. Four groups of rats were set, including eight subjects each as Group 1 (control), Group 2-RIR (renal isc...