Extraskeletal Ewing's Sarcoma: insight into a ten years follow-up

• Published in: Clinica terapeutica Vol. 164; no. 5; p. e373
• Main Authors: Zitelli, A, Manfredelli, S, Brunotti, G, Marcantonio, M, Pontone, S, Angelici, A
• Format: Journal Article
• Language: English
• Published: Italy 2013
• Subjects: Abdominal Neoplasms - diagnostic imaging; Abdominal Neoplasms - pathology; Abdominal Neoplasms - therapy; Abdominal Pain - etiology; Adult; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biomarkers, Tumor - analysis; Chemotherapy, Adjuvant; Combined Modality Therapy; Doxorubicin - administration & dosage; Etoposide - administration & dosage; Female; Follow-Up Studies; Humans; Ifosfamide - administration & dosage; Intestines - surgery; Radiotherapy, Adjuvant; Rupture, Spontaneous; Sarcoma, Ewing - diagnostic imaging; Sarcoma, Ewing - pathology; Sarcoma, Ewing - therapy; Survivors; Tomography, X-Ray Computed; Vincristine - administration & dosage
• ISSN: 1972-6007
• DOI: 10.7417/CT.2013.1615

Extraskeletal Ewing's sarcoma is a rare malignant soft tissue tumor, classified within the Ewing's Sarcoma Family Tumors. While the classical Ewing's Sarcoma affects mainly the bone during youth, the Extraskeletal histotype differs for age incidence, primary location and prognosis. Peak incidence and typical location are during adolescence and in the extremities respectively. We report a 30 year old woman case with a positive outcome after ten years from first diagnosis of Extraskeletal Ewing's sarcoma. Treatment was achieved through surgical resection plus adjuvant chemoradiotherapy derived from EW93 and IRS III trials. Conclusion. Our report represents an unusual case due to age of presentation, neoplasm location and long survival reached. In last decades several trials results demonstrated that long survival could be achieved by combined surgery and adjuvant multi-drug treatment.