Can preterm birth be prevented from ascending bacterial infection and its adverse results in the public hospitals of Chile?

Preterm birth (PB) is the main contributor to the perinatal morbidity/mortality. In spite of the knowledge of the risk factors and the introduction of medical interventions intended to prevent PB, its frequency has increased. Ascending bacterial infection (ABI) is the obstetric condition most freque...

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Bibliographic Details
Published inRevista chilena de infectología Vol. 36; no. 3; pp. 358 - 368
Main Authors Ovalle, Alfredo, Martínez, María Angélica, Figueroa, Jorge
Format Journal Article
LanguageSpanish
Published Chile 01.06.2019
Subjects
Bacterial Infections - complications
Bacterial Infections - prevention & control
Chile
Female
Hospitals, Public
Humans
Pregnancy
Pregnancy Complications, Infectious - immunology
Pregnancy Complications, Infectious - physiopathology
Premature Birth - etiology
Premature Birth - prevention & control
Reproductive Tract Infections - complications
Reproductive Tract Infections - immunology
Reproductive Tract Infections - physiopathology
Risk Factors
Chile
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Summary:Preterm birth (PB) is the main contributor to the perinatal morbidity/mortality. In spite of the knowledge of the risk factors and the introduction of medical interventions intended to prevent PB, its frequency has increased. Ascending bacterial infection (ABI) is the obstetric condition most frequently associated to PB causing an important adverse perinatal outcome in a public hospital in Chile. This review shows the association between PB and ABI, analyzes the physiopathology and immunology of vaginal infections in the susceptible pregnant woman., as well as their application in this group of effective measures demonstrated by evidence, such as routine control, treatment of genitourinary tract infections (GTI), prophylactic or therapeutic cerclage, use of probiotics, use of vaginal progesterone, metabolic control of diabetes mellitus and weight of the obese woman. Treatment GTI together with the use of medical interventions that improve the vaginal immunity in the risk population allow to predict a reduction of PB by ABI and of its immediate consequences, long term sequels and high associated costs, with the consequent benefit of the public health in Chile.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0717-6341
DOI:10.4067/S0716-10182019000300358