Sleep deprivation, oxidative stress and inflammation

Adequate sleep is essential for normal brain function, especially during early life developmental stages as postnatal brain maturation occurs during the critical period of childhood and adolescence. Therefore, sleep disturbance and/or deficit during this period can have detrimental consequences. Man...

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Bibliographic Details
Published inAdvances in protein chemistry and structural biology Vol. 119; p. 309
Main Authors Atrooz, Fatin, Salim, Samina
Format Journal Article
LanguageEnglish
Published Netherlands 2020
Subjects
Animals
Brain - metabolism
Humans
Inflammation - metabolism
Oxidative Stress
Sleep Deprivation - metabolism
Oxidative stress
Inflammation
Sleep
Stress
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Summary:Adequate sleep is essential for normal brain function, especially during early life developmental stages as postnatal brain maturation occurs during the critical period of childhood and adolescence. Therefore, sleep disturbance and/or deficit during this period can have detrimental consequences. Many epidemiological and clinical studies have linked early life sleep disturbance with occurrence of later life behavioral and cognitive impairments. Role of oxidative stress and inflammation has been implicated in sleep deprivation-related impairments. This review article presents a detailed description of the current state of the literature on the subject.
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ISSN:1876-1631
1876-1631
DOI:10.1016/bs.apcsb.2019.03.001