Memantine in the treatment and prophylaxis of bipolar type II mood disorder and co-morbid eating disorder: a case report

• Published in: Rivista di psichiatria Vol. 49; no. 4; p. 192
• Main Authors: De Chiara, Lavinia, Serra, Giulia, Koukopoulos, Alexia Emilia, Koukopoulos, Athanasios, Serra, Gino
• Format: Journal Article
• Language: English
• Published: Italy 01.07.2014
• Subjects: Adult; Antimanic Agents - therapeutic use; Bipolar Disorder - classification; Bipolar Disorder - complications; Bipolar Disorder - drug therapy; Bipolar Disorder - prevention & control; Feeding and Eating Disorders - complications; Female; Humans; Memantine - therapeutic use; Mood Disorders - classification; Mood Disorders - complications; Mood Disorders - drug therapy; Mood Disorders - prevention & control
• ISSN: 2038-2502
• DOI: 10.1708/1600.17462

We have recently reported that memantine has a clinically relevant antimanic and long-lasting mood-stabilizing effect in treatment- resistant bipolar disorders, both as augmenting agent and as a monotherapy. Moreover, we observed an acute antimanic and sustained mood-stabilizing effect also in "naïve" bipolar type I disorder. Here we report a case history of a young woman suffering from bipolar type II mood disorder, associated with a very severe eating disorder, showing an acute antimanic and a long-term prophylactic effect of memantine on bipolar disorder and comorbid eating disorder.