Fetal Pancreatic Stem-Cell Transplant in Patients With Diabetes Mellitus
To determine the efficacy of fetal stem cell transplant for treating patients with diabetes mellitus types 1 and 2. Five patients with diabetes mellitus type 1 and 5 patients with diabetes mellitus type 2 (aged 18-56 years) received a fetal pancreatic stem-cell transplant (cells were 16-18 wk gestat...
Saved in:
Published in | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation Vol. 13 Suppl 3; pp. 160 - 162 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Turkey
01.11.2015
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | To determine the efficacy of fetal stem cell transplant for treating patients with diabetes mellitus types 1 and 2.
Five patients with diabetes mellitus type 1 and 5 patients with diabetes mellitus type 2 (aged 18-56 years) received a fetal pancreatic stem-cell transplant (cells were 16-18 wk gestation) performed by intravenous infusion at 50 mL/hour. The quantity of fetal stem cells infused was ≥ 5-8*106. We analyzed the patients' C-peptide and glycated hemoglobin levels both before and 3 months after fetal stem cell transplant.
In patients with diabetes mellitus type 1, fetal stem-cell transplant led to a significant increase in C-peptide levels, from 0.09 ± 0.01 ng/mL to 0.20 ± 0.07 ng/mL, after 3 months (P < .008).
Treatment with fetal pancreatic stem cells may be beneficial for treating patients with type 1 or type 2 diabetes. |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2146-8427 |
DOI: | 10.6002/ect.tdtd2015.P89 |