Tolerability and cosmetic acceptability of a body wash in atopic dermatitis-prone subjects

Atopic dermatitis is a common skin disease characterized by eczematous eruptions and impaired skin barrier function. Patients, as well as their families, frequently report reductions in quality of life. Pruritus, lack of sleep, and impaired social functioning all contribute to this reduction. A skin...

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Bibliographic Details
Published inJournal of drugs in dermatology Vol. 13; no. 9; p. 1108
Main Authors Brandt, Staci, Meckfessel, Matthew H, Lio, Peter A
Format Journal Article
LanguageEnglish
Published United States 01.09.2014
Subjects
Adolescent
Adult
Aged
Child
Child, Preschool
Cosmetics - administration & dosage
Dermatitis, Atopic - diagnosis
Dermatitis, Atopic - psychology
Dermatitis, Atopic - therapy
Drug Combinations
Female
Humans
Male
Middle Aged
Propylene Glycols - administration & dosage
Quality of Life - psychology
Skin Care - methods
Soaps - administration & dosage
Sodium Dodecyl Sulfate - administration & dosage
Young Adult
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ISSN1545-9616

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Summary:Atopic dermatitis is a common skin disease characterized by eczematous eruptions and impaired skin barrier function. Patients, as well as their families, frequently report reductions in quality of life. Pruritus, lack of sleep, and impaired social functioning all contribute to this reduction. A skincare regimen of gentle cleansing and daily moisturization is integral to managing atopic dermatitis. While there are a multitude of reports supporting the use of moisturizers, there is a paucity regarding the use of cleansers, especially cleansers formulated with ingredients known to improve skin hydration. A clinical study was conducted to assess the tolerability and cosmetic acceptability of a body wash formulated with the filaggrin break-down products arginine and pyrrolidone carboxylic acid in subjects with atopic dermatitis-prone skin (Cetaphil® RestoraDerm® Body Wash). The results of this study indicate that Cetaphil RestoraDerm Body Wash was well tolerated, reduced itch, improved quality of life, and was well-liked by subjects with atopic dermatitis-prone skin.
ISSN:1545-9616