Population genetic structure of malaria vector Anopheles stephensi Liston (Diptera: Culicidae)

• Published in: Indian journal of experimental biology Vol. 51; no. 4; pp. 273 - 279
• Main Authors: Gakhar, S K, Sharma, Richa, Sharma, Arvind
• Format: Journal Article
• Language: English
• Published: India 01.04.2013
• Subjects: Animals; Anopheles - genetics; DNA, Mitochondrial - genetics; DNA, Ribosomal - genetics; Genetic Markers - genetics; Genetics, Population; Geography; Humans; India; Insect Vectors - genetics; Insecticide Resistance - genetics; Malaria - parasitology; Malaria - prevention & control; Microsatellite Repeats - genetics; Pakistan; Random Amplified Polymorphic DNA Technique; Pakistan; India
• ISSN: 0019-5189

Malaria is a complex disease that afflicts human today. Malaria epidemiology is associated with drug resistance in parasite and differential distribution and insecticide resistance in vector. Efforts are being made to eradicate malaria but burden of malaria is still increasing. Vector control is essential for malaria prevention strategies. Knowledge of population genetic structure is pre-requisite for determining prevention strategies particularly using transgenic mosquitoes. Population genetic study can predict level of gene flow between different populations. Anopheles stephensi Liston is urban vector of malaria in Indo-Pakistan subcontinent. About 12% of malaria cases of malaria in India are contributed by A. stephensi. Studies conducted on population genetics of A. stephensi using various markers in different parts of the world are discussed in this communication.