Epidemiology and risk factors of schizophrenia

Schizophrenia is a severe mental disorder that affects approximately one percent of the general population. The pathogenesis of schizophrenia is influenced by many risk factors, both environmental and genetic. The environmental factors include the date of birth, place of birth and seasonal effects,...

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Bibliographic Details
Published inNeuro-endocrinology letters Vol. 37; no. 1; p. 1
Main Authors Janoutová, Jana, Janácková, Petra, Serý, Omar, Zeman, Tomás, Ambroz, Petr, Kovalová, Martina, Varechová, Katerina, Hosák, Ladislav, Jirík, Vitezslav, Janout, Vladimír
Format Journal Article
LanguageEnglish
Published Sweden 2016
Subjects
Environment
Female
Genetic Predisposition to Disease
Humans
Infant, Newborn
Parturition - physiology
Pregnancy
Prevalence
Risk Factors
Schizophrenia - epidemiology
Schizophrenia - etiology
Substance-Related Disorders - complications
Substance-Related Disorders - epidemiology
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Summary:Schizophrenia is a severe mental disorder that affects approximately one percent of the general population. The pathogenesis of schizophrenia is influenced by many risk factors, both environmental and genetic. The environmental factors include the date of birth, place of birth and seasonal effects, infectious diseases, complications during pregnancy and delivery, substance abuse and stress. At the present time, in addition to environmental factors, genetic factors are assumed to play a role in the development of the schizophrenia. The heritability of schizo- phrenia is up to 80%. If one parent suffers from the condition, the probability that it will be passed down to the offspring is 13%. If it is present in both parents, the risk is more than 20%. The opinions are varied as to the risk factors affecting the development of schizophrenia. Knowing these factors may greatly contribute to prevention of the condition.
ISSN:0172-780X