Effect of the presence of a drug in the list of supplementary drug provision on compliance to its administration by outpatients with arterial hypertension

• Published in: Kardiologiia Vol. 51; no. 6; p. 21
• Main Authors: Ageev, F T, Fofanova, T V, Kadushina, E B, Deev, A D, Kuz'mina, A E, Patrusheva, I F
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2011
• Subjects: Age Factors; Antihypertensive Agents - economics; Antihypertensive Agents - therapeutic use; Attitude to Health; Blood Pressure Monitoring, Ambulatory - economics; Blood Pressure Monitoring, Ambulatory - instrumentation; Cost of Illness; Female; Humans; Hypertension - diagnosis; Hypertension - drug therapy; Hypertension - economics; Hypertension - psychology; Life Style; Male; Medical Assistance - organization & administration; Medication Adherence - psychology; Medication Adherence - statistics & numerical data; Middle Aged; Outpatients - psychology; Outpatients - statistics & numerical data; Risk Factors; Sex Factors; Sickness Impact Profile; Sphygmomanometers - economics
• ISSN: 0022-9040

Aim of the study was to investigate relationship between the presence of a drug in the list of supplementary drug provision (SDP) and compliance to its consumption by outpatients with arterial hypertension as well as determination of the place of SDP in a row of other factors affecting compliance to treatment. Methods. Patients (men and women) older than 18 years with initial level of office systolic arterial pressure (AP) 140-179 mm Hg and diastolic AP up to 100 mm Hg who visited regional internist. The study was conducted at the base of 82 Moscow polyclinics with participation of 185 physicians and 5474 patients. In all patients besides general clinical examination with office AP measurement calculation of body mass index and assessment of risk factors and concomitant therapy were carried out. All patients assessed themselves their self feeling with the use of visual-analog scale (VAS). Compliance of patients to antihypertensive therapy was evaluated with the help of the Moriski - Green test. Fact of continuous use of antihypertensive drugs received by patients within framework of the SDP system was necessarily obligatory. For final analysis 4816 ambulatory cards were selected. Results. Portion of patients with low compliance to therapy was greatly than that of patients with high compliance to therapy (61.1 vs. 38.9%, respectively, p=0.00001). Inclusion into analysis of additional factor (presence of CHD) reduced contribution of SDP to compliance to 25%, but it remained as before significant (p<0.0007). However addition to these factors of other parameters such as presence of diabetes mellitus or tonometer at home completely leveled effect of SDP on compliance to therapy (p<0.12). Conclusion. Presence of drugs in the SDP list significantly elevates compliance to therapy. However SDP does not appear the only independent predictor of high compliance. If SDP is considered together with other determining factors (presence of concomitant IHD and diabete, readiness to spend money for tonometer) its role as independent factor of high compliance is diminished and loses significance.