Carcinoma ex pleomorphic adenoma in a minor salivary gland: report of a case

• Published in: Oral and maxillofacial surgery Vol. 14; no. 1; pp. 59 - 62
• Main Authors: Reichart, Peter A., Kalz, Steffen, Rabel, Annette, Bornstein, Michael M.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.03.2010; Springer Nature B.V
• Subjects: Adenoma, Pleomorphic - pathology; Adenoma, Pleomorphic - surgery; Carcinoma - pathology; Carcinoma - surgery; Case Report; Cheek; Dentistry; Humans; Lip; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Invasiveness; Neoplasms, Multiple Primary - pathology; Neoplasms, Multiple Primary - surgery; Oral and Maxillofacial Surgery; Reoperation; Salivary Gland Neoplasms - pathology; Salivary Gland Neoplasms - surgery; Salivary Glands, Minor - pathology; Salivary Glands, Minor - surgery; Minor salivary gland tumor; Pleomorphic adenoma; Carcinoma ex pleomorphic adenoma
• ISSN: 1865-1550; 1865-1569
• DOI: 10.1007/s10006-009-0183-3

Background Carcinoma ex pleomorphic adenoma is exceedingly rare in minor salivary glands of the oral cavity. We present a case of carcinoma ex pleomorphic adenoma (CEPA) of the buccal mucosa in a 47-year-old Turkish patient. The buccal mass was of a size of 1.5 cm located in the left cheek. Pleomorphic adenoma was the tentative diagnosis. Methods The tumor was removed under local anesthesia. Histopathologic evaluation revealed a preexisting pleomorphic adenoma associated with adenoid tumor component with tubulo-cystic and papillary or pseudopapillary structures; CEPA was diagnosed. Capsular integrity was incomplete with infiltration by islands of metaplastic/dysplastic epithelium. Results Secondary surgery of the site was performed. No tumor tissue could be detected in the resection specimen. The patient is free of recurrence since 9 months.