D-penicillamine, a potent melanogenesis inhibitor, lacks any depigmenting effect on black guinea pig skin: the first randomized, evaluator-blinded, vehicle-controlled, in vivo study

D-penicillamine is a melanogenesis inhibitor. This in vivo study on ten black guinea pigs using a 5% D-penicillamine ointment showed its lack of any skin-lightening effect. The potential reasons for this ineffectiveness are discussed in the paper, which could be very helpful for researchers explorin...

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Published inActa dermatovenerologica Alpina, Panonica, et Adriatica Vol. 20; no. 2; pp. 51 - 53
Main Authors Sharifian, Maryam, Sari-Aslani, Fatemeh, Hemmatinejad, Bahram, Fallahzadeh, Mohammad K, Kasraee, Behrooz, J Khoshandish, Mohammad, Miri, Ramin, Mohammadi-Samani, Soleyman, Jowkar, Farideh, Namazi, Mohammad R
Format Journal Article
LanguageEnglish
Published Slovenia 01.06.2011
Subjects
Animals
Guinea Pigs
Penicillamine - pharmacology
Random Allocation
Skin Pigmentation - drug effects
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Summary:D-penicillamine is a melanogenesis inhibitor. This in vivo study on ten black guinea pigs using a 5% D-penicillamine ointment showed its lack of any skin-lightening effect. The potential reasons for this ineffectiveness are discussed in the paper, which could be very helpful for researchers exploring new skin-lightening agents.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1581-2979