Confirmation of safety and therapeutic effect of betaxolol in the treatment of mild and moderate hypertension in general medical practice

Data on office blood pressure (BP) and pulse rate as well as information on adverse effects were collected from 148 patients with mild and moderate hypertension during 12 week treatment with long acting lipophilic selective beta-adrenoreceptor blocker betaxolol (20 mg/day). BP normalization was achi...

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Bibliographic Details
Published inKardiologiia Vol. 45; no. 10; p. 12
Main Authors Belousov, Iu B, Egorova, N A, Sidorenko, B A, Ivleva, A Iu, Ageev, F T, Oleĭnikov, V E
Format Journal Article
LanguageRussian
Published Russia (Federation) 2005
Subjects
Adrenergic beta-Antagonists - adverse effects
Adrenergic beta-Antagonists - therapeutic use
Adult
Betaxolol - adverse effects
Betaxolol - therapeutic use
Female
Humans
Hypertension - diagnosis
Hypertension - drug therapy
Male
Middle Aged
Primary Health Care
Severity of Illness Index
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Summary:Data on office blood pressure (BP) and pulse rate as well as information on adverse effects were collected from 148 patients with mild and moderate hypertension during 12 week treatment with long acting lipophilic selective beta-adrenoreceptor blocker betaxolol (20 mg/day). BP normalization was achieved in 72.5% and in 16.8% of patients BP was lowered more than 10% without achievement of target values. Pulse rate lowering by more than 15 beats/min occurred in 40.3% of patients. Combined therapy was required in 15.2% of patients. Adverse effects specific for the class of beta-adrenoblockers caused cessation of betaxolol therapy in 3 patients. The drug was found ineffective in 4 patients (2.7%). Thus we confirmed high clinical efficacy and good safety and tolerability of betaxolol in patients with mild and moderate hypertension.
ISSN:0022-9040