The significance of Doppler flow in early detection of uterine sarcoma in older primigravida pregnancies

During a four-year period we analyzed the significance, sensitivity and sensibility of myoma Doppler flow during pregnancy in relation to the course and outcome of the pregnancy and to later histopathological findings. By following 36 older primigravidas with determined myomas, we observed the cours...

Full description

Saved in:
Bibliographic Details
Published inEuropean journal of gynaecological oncology Vol. 26; no. 3; p. 291
Main Authors Gojnic, M, Likic, I, Pervulov, M, Petkovic, S, Fazlagic, A, Vasiljevic, B
Format Journal Article
LanguageEnglish
Published Italy 2005
Subjects
Adult
Age Factors
Female
Gravidity
Gynecologic Surgical Procedures
Humans
Leiomyoma - diagnostic imaging
Leiomyoma - surgery
Leiomyosarcoma - diagnostic imaging
Leiomyosarcoma - surgery
Pregnancy
Pregnancy Complications, Neoplastic - diagnostic imaging
Pregnancy Complications, Neoplastic - surgery
Ultrasonics
Ultrasonography
Uterine Neoplasms - diagnostic imaging
Uterine Neoplasms - surgery
Online AccessGet more information

Cover

More Information
Summary:During a four-year period we analyzed the significance, sensitivity and sensibility of myoma Doppler flow during pregnancy in relation to the course and outcome of the pregnancy and to later histopathological findings. By following 36 older primigravidas with determined myomas, we observed the course of the pregnancies in all trimesters and analyzed myoma Doppler flow. In conditions where the resistance index showed the possibility of uterine sarcoma, the pregnancy was ended by surgery; not only was myomectomy performed but also complete uterine hysterectomy with the previous consent of the patient. Doppler flow was accepted as the authoritative parameter for non-invasive detection of a malignant process. Considering the obstetrical findings, other patients were delivered vaginally or operatively, but after puerperium they were subjected to control examinations and myomectomy because Doppler flow findings did not show any indications of sarcoma. By histopathological analysis, we received benign results in 31 cases, while in four cases where we decided on hysterectomy and surgical delivery, we received malignant results, i.e. leiomyosarcoma. In four cases of performed hysterectomy immediately after cesarean section, the resistance index (RI) of revascularization within the myoma was in the range between RI 0.30 +/- 0.02. Flows within the uterine artery were 0.54 +/- 0.03.
ISSN:0392-2936