A unique case of palatinate tonsil metastasis from endometrial cancer

Metastases from malignancies of the female genital tract to the tonsils have never been reported. A case of a 55-year-old woman presenting with a palatinate tonsil tumour two and half years after primary diagnosis of endometrioid endometrial adenocarcinoma (FIGO Stage IB, G2) and six months after lo...

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Published inEuropean journal of gynaecological oncology Vol. 30; no. 2; p. 229
Main Authors Zepiridis, L, Zafrakas, M, Theodoridis, T D, Kaplanis, K, Dinas, K K, Bontis, J N
Format Journal Article
LanguageEnglish
Published Italy 2009
Subjects
Adenocarcinoma - secondary
Endometrial Neoplasms - pathology
Female
Humans
Middle Aged
Tonsillar Neoplasms - secondary
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Summary:Metastases from malignancies of the female genital tract to the tonsils have never been reported. A case of a 55-year-old woman presenting with a palatinate tonsil tumour two and half years after primary diagnosis of endometrioid endometrial adenocarcinoma (FIGO Stage IB, G2) and six months after local disease recurrence is presented. The tonsillar malignancy was poorly differentiated and tumour cells were immunohistochemically positive to LMW keratin and EMA, and negative to HMW keratin and LCA, strongly suggesting a possible endometrial origin of the tumour. Metastatic disease was treated with systemic chemotherapy, but the patient soon succumbed due to rapid disease progression. In conclusion, a unique case of a palatinate tonsil tumour as the first metastatic site in an endometrial cancer patient is reported.
ISSN:0392-2936