Follicular dendritic cell sarcoma in the lymph nodes of the neck
Follicular dendritic cell sarcoma (FDCS) is a rare tumor, derived from antigen-presenting cells that normally form meshworks in lymphoid follicles. FDCS in general recapitulate the immunophenotypic profile of follicular dendritic cells (FDCs). This tumor affects mainly the lymph nodes, but may arise...
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Published in | Bratislavské lékarské listy Vol. 108; no. 8; p. 368 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Slovakia
2007
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Subjects | |
Online Access | Get more information |
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Summary: | Follicular dendritic cell sarcoma (FDCS) is a rare tumor, derived from antigen-presenting cells that normally form meshworks in lymphoid follicles. FDCS in general recapitulate the immunophenotypic profile of follicular dendritic cells (FDCs). This tumor affects mainly the lymph nodes, but may arise at a variety of extranodal sites in about one third of cases. We present a case of FDCS in a 52-year-old woman with left neck mass. Histologically, the tumor was composed of oval-to-spindle cells arranged in a fascicular and storiform pattern. Immunohistochemically, the tumor cells were positive for CD21, CD35, and to a lesser extent for EMA and vimentin (Fig. 3, Ref. 14). Full Text (Free, PDF) www.bmj.sk. |
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ISSN: | 0006-9248 |