Follicular dendritic cell sarcoma in the lymph nodes of the neck

Follicular dendritic cell sarcoma (FDCS) is a rare tumor, derived from antigen-presenting cells that normally form meshworks in lymphoid follicles. FDCS in general recapitulate the immunophenotypic profile of follicular dendritic cells (FDCs). This tumor affects mainly the lymph nodes, but may arise...

Full description

Saved in:
Bibliographic Details
Published inBratislavské lékarské listy Vol. 108; no. 8; p. 368
Main Authors Zivkovic, V, Basic, M, Gligorijevic, J, Pavlovic, V, Lazarevic, V, Petrovic, A
Format Journal Article
LanguageEnglish
Published Slovakia 2007
Subjects
Online AccessGet more information

Cover

Loading…
More Information
Summary:Follicular dendritic cell sarcoma (FDCS) is a rare tumor, derived from antigen-presenting cells that normally form meshworks in lymphoid follicles. FDCS in general recapitulate the immunophenotypic profile of follicular dendritic cells (FDCs). This tumor affects mainly the lymph nodes, but may arise at a variety of extranodal sites in about one third of cases. We present a case of FDCS in a 52-year-old woman with left neck mass. Histologically, the tumor was composed of oval-to-spindle cells arranged in a fascicular and storiform pattern. Immunohistochemically, the tumor cells were positive for CD21, CD35, and to a lesser extent for EMA and vimentin (Fig. 3, Ref. 14). Full Text (Free, PDF) www.bmj.sk.
ISSN:0006-9248