The small world in biophysical systems structural properties of glycolysis and the TCA cycle in Escherichia coli

It has been shown that the central metabolic network of Escherichia coli is of the small-world type. In this paper, we present that the metabolic network of glycolysis and TCA cycle as a part of the E. coli metabolism is also a small-world network. We found that the hubs of the studied network are c...

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Bibliographic Details
Published inCellular & molecular biology letters Vol. 7; no. 1; pp. 129 - 131
Main Authors Krajnc, Borut, Marhl, Marko
Format Journal Article
LanguageEnglish
Published England 2002
Subjects
Biological Evolution
Biophysical Phenomena
Biophysics
Citric Acid Cycle
Escherichia coli - metabolism
Glycolysis
Substrate Specificity
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Summary:It has been shown that the central metabolic network of Escherichia coli is of the small-world type. In this paper, we present that the metabolic network of glycolysis and TCA cycle as a part of the E. coli metabolism is also a small-world network. We found that the hubs of the studied network are consistent with those found in the complete metabolic network. The evolutionary meaning of this finding is discussed.
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ISSN:1425-8153