A novel technique with a flexible applicator for MRI-based brachytherapy of cervical cancer

To introduce a novel technique for magnetic resonance (MR)-based 3-dimensional planned high-dose rate intracervical brachytherapy (BT). During 2002, 16 patients received external beam radiotherapy and BT as part of radiochemotherapy for cervical cancer. A special adjustable applicator device was des...

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Bibliographic Details
Published inEuropean journal of gynaecological oncology Vol. 25; no. 3; p. 347
Main Authors Hadjiev, J, Antal, G, Antalffy, Z, Bogner, P, Esik, O, Repa, I
Format Journal Article
LanguageEnglish
Published Italy 2004
Subjects
Adult
Aged
Brachytherapy - instrumentation
Brachytherapy - methods
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - radiotherapy
Equipment Design
Female
Humans
Magnetic Resonance Imaging - instrumentation
Magnetic Resonance Imaging - methods
Middle Aged
Radiology, Interventional - instrumentation
Radiology, Interventional - methods
Radiotherapy Dosage
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - radiotherapy
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Summary:To introduce a novel technique for magnetic resonance (MR)-based 3-dimensional planned high-dose rate intracervical brachytherapy (BT). During 2002, 16 patients received external beam radiotherapy and BT as part of radiochemotherapy for cervical cancer. A special adjustable applicator device was designed and used for BT. The isodose distribution was calculated from MR images with the applicator in place. The planning target volume coverage was adequate and the radiation burden on the organs at risk was within acceptable limits. Complete regression was achieved in two patients (12.5%), and partial regression in ten (62.5%) patients. The overall response rate for the complex treatment was 93.75%. In three cases the disease was considered to be stable. The MR-compatible, flexible applicator allows safe and reproducible cervical radiotherapy with no added discomfort or hazard for the patient.
ISSN:0392-2936