Effect of fluoridated dentifrice and acidulated phosphate fluoride application on early artificial carious lesions

To evaluate the effect of a combination of fluoride dentifrice and acidulated phosphate fluoride (APF) on enamel with incipient caries lesions. Bovine dental enamel blocks with artificial caries lesions were divided into four treatment groups and submitted to a pH-cycling model: (1) Placebo non-fluo...

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Bibliographic Details
Published inAmerican journal of dentistry Vol. 16; no. 2; p. 91
Main Authors Paes Leme, Adriana Franco, Tabchoury, Cinthia Pereira Machado, Zero, Domenick Thomas, Cury, Jaime Aparecido
Format Journal Article
LanguageEnglish
Published United States 01.04.2003
Subjects
Acidulated Phosphate Fluoride - therapeutic use
Analysis of Variance
Animals
Cariostatic Agents - administration & dosage
Cariostatic Agents - pharmacokinetics
Cariostatic Agents - therapeutic use
Cattle
Dental Caries - drug therapy
Dental Enamel - metabolism
Dental Enamel Solubility
Dentifrices - chemistry
Fluorides - administration & dosage
Fluorides - pharmacokinetics
Fluorides - therapeutic use
Hardness
Saliva - chemistry
Statistics, Nonparametric
Tooth Remineralization
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Summary:To evaluate the effect of a combination of fluoride dentifrice and acidulated phosphate fluoride (APF) on enamel with incipient caries lesions. Bovine dental enamel blocks with artificial caries lesions were divided into four treatment groups and submitted to a pH-cycling model: (1) Placebo non-fluoridated dentifrice (PD); (2) Fluoridated dentifrice (FD), 1,100 ppm F; (3) APF (12,300 ppm F, pH 3.5) + PD; 4) APF+FD. APF was applied to enamel blocks of groups APF+PD and APF+FD before the pH-cycling regimen and all of them were exposed to dentifrice during the cycling. The results showed that 61-81% of the fluoride previously deposited in enamel by APF was released to the media during the pH-cycling. The final concentration of fluoride in enamel in the group APF+PD was lower than that before the cycling (P < 0.05), but in the group APF+FD the reduction was not significant (P> 0.05). FD treatment was significantly more efficient than PD in rehardening the enamel surface and increasing the hardness of the caries lesions. APF+PD treatment was not more efficient than PD in increasing enamel hardness and an additive effect of APF+FD was not observed.
ISSN:0894-8275