Measuring the efficacy of rhBMP-2 to regenerate bone: a radiographic study using a commercially available software program

• Published in: The International journal of periodontics & restorative dentistry Vol. 24; no. 6; p. 579
• Main Authors: Bianchi, Jorge, Fiorellini, Joseph P, Howell, T Howard, Sekler, Julio, Curtin, Hugh, Nevins, Marc L, Friedland, Bernard
• Format: Journal Article
• Language: English
• Published: United States 01.12.2004
• Subjects: Alveolar Bone Loss - surgery; Alveolar Process - diagnostic imaging; Alveolar Process - drug effects; Alveolar Ridge Augmentation; Bone Density - drug effects; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins - therapeutic use; Bone Regeneration - drug effects; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted - methods; Male; Maxilla - diagnostic imaging; Maxilla - drug effects; Maxilla - surgery; Middle Aged; Reproducibility of Results; Retrospective Studies; Software; Tomography, X-Ray Computed; Transforming Growth Factor beta - therapeutic use

This radiographic study evaluated the efficacy of different concentrations of rhBMP-2 to regenerate bone in alveolar defects in the anterior maxilla. The study was performed using reasonably standardized CT examinations and the Simplant program. The radiographic measurements were further refined by...