Preparation of primary amine-modified gold nanoparticles and their transfection ability into cultivated cells

Cationic gold nanoparticles, prepared by reducing HAuCl(4) with NaBH(4) in the presence of 2-aminoethanethiol, formed a complex with plasmid DNA, and could be transfected into cultivated cells.

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Bibliographic Details
Published inChemical communications (Cambridge, England) no. 17; pp. 1978 - 1979
Main Authors Niidome, Takuro, Nakashima, Kanako, Takahashi, Hironobu, Niidome, Yasuro
Format Journal Article
LanguageEnglish
Published England 07.09.2004
Subjects
Amines - chemistry
Animals
Borohydrides - chemistry
Cells, Cultured
CHO Cells
Cricetinae
Cysteamine - chemistry
DNA - chemistry
DNA - genetics
Electrophoresis, Agar Gel
Gold - chemistry
Microscopy, Electron, Transmission
Nanostructures
Plasmids - genetics
Transfection - methods
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Summary:Cationic gold nanoparticles, prepared by reducing HAuCl(4) with NaBH(4) in the presence of 2-aminoethanethiol, formed a complex with plasmid DNA, and could be transfected into cultivated cells.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
DOI:10.1039/b406189f