Chemical sterilization with an IUD

Zipper has more than adequately demonstrated that quinacrine, when placed in the uterine cavity, has a sclerosing effect on the tubal ostia, resulting in chemical sterilization of the fallopian tubes. His technique involves the use of 3 monthly instillations of 250 mg of pellets into the uterine cav...

Full description

Saved in:
Bibliographic Details
Published inContraceptive delivery systems Vol. 2; no. 4; p. 343
Main Author Laufe, L E
Format Journal Article
LanguageEnglish
Published England 01.10.1981
Subjects
Chemical Phenomena
Chemistry
Chemosterilants
Contraception
Family Planning Services
General Surgery
Gynecologic Surgical Procedures
Intrauterine Devices
Pharmaceutical Preparations
Polyethylene
Polymers
Quinacrine
Sterilization, Reproductive
Sterilization, Tubal
Therapeutics
Drugs
Polyethylene
Quinacrine
Contraception
Urogenital Surgery
Family Planning
Gynecologic Surgery
Chemosterilants
Tubal Occlusion
Treatment
Female Sterilization
Surgery
Contraceptive Methods
Iud
Sterilization, Sexual
Ingredients And Chemicals
Polymers
Online AccessGet more information

Cover

More Information
Summary:Zipper has more than adequately demonstrated that quinacrine, when placed in the uterine cavity, has a sclerosing effect on the tubal ostia, resulting in chemical sterilization of the fallopian tubes. His technique involves the use of 3 monthly instillations of 250 mg of pellets into the uterine cavity. With the hope of reducing the total dosage and making it a 1-insertion technique, quinacrine has been mixed with polyethylene oxide and place on the arms of various IUDs. It is hoped that the material is directed at the tubal ostia. Studies to date have occurred in women awaiting hysterectomy with careful pathologic examination of the intramural portion of the tube. The results thus far are most encouraging and once the best vector is identified, it is hoped that this will become an acceptable means of female sterilization.
ISSN:0143-6112