First report of lymphatic mapping with isosulfan blue dye and sentinel node biopsy in cervical cancer

Sentinel lymph node status provides important information about the status of the regional nodes in various malignant tumors. Our report describes a method of identifying the sentinel lymph nodes in cervical cancer. In three cases of early cervical cancer, isosulfan blue dye was injected paracervica...

Full description

Saved in:
Bibliographic Details
Published inAnticancer research Vol. 20; no. 2B; p. 1133
Main Authors Medl, M, Peters-Engl, C, Schütz, P, Vesely, M, Sevelda, P
Format Journal Article
LanguageEnglish
Published Greece 01.03.2000
Subjects
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Aged
Biopsy
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Female
Humans
Lymph Node Excision
Lymph Nodes - pathology
Lymphatic Metastasis - pathology
Middle Aged
Neoplasm Staging
Rosaniline Dyes
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - surgery
Online AccessGet more information

Cover

More Information
Summary:Sentinel lymph node status provides important information about the status of the regional nodes in various malignant tumors. Our report describes a method of identifying the sentinel lymph nodes in cervical cancer. In three cases of early cervical cancer, isosulfan blue dye was injected paracervically into each lateral fornix immediately before surgery. In all cases we identified two to three blue stained (sentinel) lymph nodes located either at the iliac artery or in the obturatory space. The blue colored nodes were positive for disease, all other pelvic lymph nodes removed were negative. Our findings demonstrate that preoperative lymphatic mapping with vital blue dye is an easy to perform technique to visualize sentinel lymph nodes in cervical cancer. Sentinel lymph node status may be representative of the pelvic lymph node status in cervical cancer and thus could provide important information for further treatment.
ISSN:0250-7005