Significance of toxic interactions in medicolegal evidence. Complex fatal poisoning with drugs of abuse in the material of the Chair of Forensic Medicine, Collegium Medicum, Jagiellonian University in Kraków

The subject of the study was fatal complex poisonings with drugs of abuse in two young men. In the first case, postmortem investigation revealed cardiotoxic death as the result of an interaction between opiates, amphetamine derivatives and oxazepam. In the second case, death followed the administrat...

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Published inPolish journal of pharmacology Vol. 53; no. 6; p. 653
Main Authors Kłys, M, Bystrowska, B, Bujak-Gizycka, B, Nowak, G
Format Journal Article
LanguageEnglish
Published Poland 01.11.2001
Subjects
Adult
Amphetamines - blood
Amphetamines - poisoning
Amphetamines - urine
Drug Interactions
Drug Overdose
Fatal Outcome
Forensic Medicine
Humans
Male
Narcotics - blood
Narcotics - poisoning
Narcotics - urine
Street Drugs - blood
Street Drugs - poisoning
Street Drugs - urine
Xenobiotics - blood
Xenobiotics - poisoning
Xenobiotics - urine
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Summary:The subject of the study was fatal complex poisonings with drugs of abuse in two young men. In the first case, postmortem investigation revealed cardiotoxic death as the result of an interaction between opiates, amphetamine derivatives and oxazepam. In the second case, death followed the administration of amphetamine derivatives and cocaine (xenobiotics known on the illicit drug market as "UFO"). Based on the toxicological postmortem analysis the authors discuss the interpretation of the results in the light of general problems of interactions taking place in toxicokinetic and toxicodynamic phases of intoxication processes.
Bibliography:ObjectType-Case Study-2
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ISSN:1230-6002