Topical therapy for acne

Acne is a common problem in adolescents and young adults. The disorder is caused by abnormal desquamation of follicular epithelium that results in obstruction of the pilosebaceous canal. This obstruction leads to the formation of comedones, which can become inflamed because of overgrowth of Propioni...

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Bibliographic Details
Published inAmerican family physician Vol. 61; no. 2; pp. 357 - 366
Main Author Russell, J J
Format Journal Article
LanguageEnglish
Published United States 15.01.2000
Subjects
Acne Vulgaris - drug therapy
Acne Vulgaris - physiopathology
Administration, Topical
Adolescent
Adult
Anti-Bacterial Agents - administration & dosage
Anti-Infective Agents, Local - administration & dosage
Benzoyl Peroxide - administration & dosage
Dermatologic Agents - administration & dosage
Dicarboxylic Acids - administration & dosage
Drug Therapy, Combination
Humans
Keratolytic Agents - administration & dosage
Patient Education as Topic
Pharmaceutical Vehicles
Retinoids - administration & dosage
Salicylic Acid - administration & dosage
Sulfacetamide - administration & dosage
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Summary:Acne is a common problem in adolescents and young adults. The disorder is caused by abnormal desquamation of follicular epithelium that results in obstruction of the pilosebaceous canal. This obstruction leads to the formation of comedones, which can become inflamed because of overgrowth of Propionibacterium acnes. Topical retinoids such as tretinoin or adapalene are effective in many patients with comedonal acne. Patients with inflammatory lesions benefit from treatment with benzoyl peroxide, azelaic acid or topical antibiotics. Frequently, the use of comedonal and antibacterial agents is required.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0002-838X