Effects of desensitizing agents on human dentin permeability

• Published in: American journal of dentistry Vol. 11; no. 6; p. 286
• Main Authors: Camps, J, Pizant, S, Dejou, J, Franquin, J C
• Format: Journal Article
• Language: English
• Published: United States 01.12.1998
• Subjects: Acid Etching, Dental; Analysis of Variance; Dentin - drug effects; Dentin - ultrastructure; Dentin Permeability - drug effects; Dentin Sensitivity - drug therapy; Dentin Sensitivity - prevention & control; Dentinal Fluid - physiology; Glutaral - pharmacology; Glutaral - therapeutic use; Humans; Materials Testing; Methacrylates - pharmacology; Methacrylates - therapeutic use; Microscopy, Electron, Scanning; Molar; Oxalates - pharmacology; Oxalates - therapeutic use; Statistics, Nonparametric; Surface Properties
• ISSN: 0894-8275

To compare the in vitro effects of three desensitizing agents on hydraulic conductance of human dentin: Protect (n = 10), Gluma Desensitizer (n = 10), MS Coat (n = 10) (Pain-Free in the USA). Dentin discs were prepared from 40 freshly extracted normal human third molars. The pulpal side of the dentin discs was etched with 37% phosphoric acid for 15 s and then rinsed under tap water. The coronal side was sequentially ground and the dentin discs were sonicated for 30 min. The hydraulic conductance was measured filtering 20% serum in phosphate buffered saline under a pressure of 15 cm H2O. The hydraulic conductance of each dentin specimen was measured before using the desensitizing agent and this value was designated as 100%. Thirty dentin discs were treated, the hydraulic conductance was remeasured and expressed as a percentage of the hydraulic conductance of that specimen before treatment. The teeth were stored for 1 month at 37 degrees C in deionized water and the hydraulic conductance of the 40 dentin discs was recorded again. Ten dentin discs were left untreated to serve as a control. No statistical difference was found between the immediate hydraulic conductance of the three groups after treatment. After 1-month storage, the control group showed a statistically higher hydraulic conductance than the three treated groups. There was no statistical difference between the three dentin desensitizing agents evaluated.