Effect of cold stress in early postnatal ontogeny on blood pressure and heart activity in normo- and hypertensive rats

Cold stress in the early postnatal ontogeny caused permanent functional changes in the cardiovascular system, which were different in hypertensive NISAG and normotensive WAG rats. Stress led to elevation of blood pressure and overload on the left heart chambers in adult WAG rats postnatally exposed...

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Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 130; no. 12; pp. 1177 - 1180
Main Authors Makhanova, N A, Markel', A L, Jacobson, G S
Format Journal Article
LanguageEnglish
Published United States 01.12.2000
Subjects
Animals
Blood Pressure
Cold Temperature - adverse effects
Electrocardiography
Heart - physiopathology
Hypertension - etiology
Hypertension - physiopathology
Male
Rats
Restraint, Physical
Stress, Physiological - complications
Stress, Physiological - physiopathology
Sympathetic Nervous System - physiopathology
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Summary:Cold stress in the early postnatal ontogeny caused permanent functional changes in the cardiovascular system, which were different in hypertensive NISAG and normotensive WAG rats. Stress led to elevation of blood pressure and overload on the left heart chambers in adult WAG rats postnatally exposed to cold. At the same time, postnatal exposure to cold stress attenuated functional disturbances typical of hypertensive NISAG rats.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-4888
DOI:10.1023/A:1017536102816