Alternative routes of insulin delivery

Parenteral route of insulin administration has been the mode of treatment for all Type 1 diabetics and Type 2 diabetics with complications. Patient compliance has really been a major concern for this route of administration. Several alternative routes of administration are under consideration for ef...

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Bibliographic Details
Published inZhong nan da xue xue bao. Journal of Central South University. Yi xue ban Vol. 34; no. 10; p. 933
Main Authors Krishnankutty, Ranjith K, Mathew, Aju, Sedimbi, Saikiran K, Suryanarayan, Shrikumar, Sanjeevi, Carani B
Format Journal Article
LanguageEnglish
Published China 01.10.2009
Subjects
Administration, Buccal
Administration, Inhalation
Administration, Intranasal
Administration, Oral
Diabetes Mellitus - drug therapy
Drug Administration Routes
Drug Delivery Systems - methods
Humans
Hypoglycemic Agents - administration & dosage
Insulin - administration & dosage
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Summary:Parenteral route of insulin administration has been the mode of treatment for all Type 1 diabetics and Type 2 diabetics with complications. Patient compliance has really been a major concern for this route of administration. Several alternative routes of administration are under consideration for effective glycemic control, including oral, inhaled, buccal, nasal, and patch routes. One of the approaches involving inhaled insulin has now reached the market. Several other candidates may reach the market in the near future, the promising one being oral insulin.
ISSN:1672-7347
DOI:10.3321/j.issn:1672-7347.2009.10.001