Amlodipine Induced Massive Ascites, a Rare Clinical Case

Calcium channel blockers (CCBs) are commonly used agents in the treatment of hypertension as part of monotherapy or combination therapy. Peripheral edema is the most common side effect that requires discontinuation or replacement of treatment. Some studies in the literature have shown that long-acti...

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Bibliographic Details
Published inIranian journal of kidney diseases Vol. 14; no. 6; p. 517
Main Authors Arasan, Sema Nur, Yenigun, Ezgi Coskun, Cevher, Simal Koksal, Dede, Fatih
Format Journal Article
LanguageEnglish
Published Iran Iranian Society of Nephrology 01.11.2020
Subjects
Abdomen
Antihypertensives
Ascites
Blood pressure
Cardiac arrhythmia
Drug dosages
Drug withdrawal
Edema
Endoscopy
Gastroenterology
Hypertension
Kidney diseases
Liver
Lupus
Nephrology
Patients
Peritoneal dialysis
Poisoning
Proteins
Pulmonary arteries
Smooth muscle
Transplants & implants
Ultrasonic imaging
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Summary:Calcium channel blockers (CCBs) are commonly used agents in the treatment of hypertension as part of monotherapy or combination therapy. Peripheral edema is the most common side effect that requires discontinuation or replacement of treatment. Some studies in the literature have shown that long-acting dihydropyridine type CCBs lead chylous ascites in peritoneal dialysis patients. However, amlodipine-associated serous ascites cases are not available in the literature. In this case report, we describe a rare case of amlodipine induced massive ascites in a 30-year-old male with renal transplantation. We aimed to create awareness that pharmacologic causes should be considered in cases of ascites of unknown aetiology.
ISSN:1735-8582
1735-8604