A correlation between arterial ketone body ratio and concentration of beta-hydroxybutyrate as an indicator of hepatic functional reserve

We have investigated the correlation between the arterial blood ketone body ratio (AKBR) and beta-hydroxybutyric acid (HBAC) in the course of a 75 g glucose tolerance test. The correlation was revealed to be represented by an equation of Y = A + BX [X = log(HBAC), Y = log(AKBR)] with high significan...

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Published inSurgery today (Tokyo, Japan) Vol. 22; no. 3; p. 244
Main Authors Hamanoue, M, Aikou, T, Tanabe, G, Takao, S, Shimazu, H, Kimotsuki, K, Nagashige, M
Format Journal Article
LanguageEnglish
Published Japan 01.01.1992
Subjects
3-Hydroxybutyric Acid
Adult
Aged
Aged, 80 and over
Biliary Tract Diseases - blood
Biliary Tract Diseases - physiopathology
Female
Glucose Tolerance Test
Humans
Hydroxybutyrates - blood
Ketone Bodies - blood
Liver - metabolism
Liver - physiopathology
Liver Diseases - blood
Liver Diseases - physiopathology
Liver Function Tests
Male
Middle Aged
Pancreatic Neoplasms - blood
Pancreatic Neoplasms - physiopathology
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Summary:We have investigated the correlation between the arterial blood ketone body ratio (AKBR) and beta-hydroxybutyric acid (HBAC) in the course of a 75 g glucose tolerance test. The correlation was revealed to be represented by an equation of Y = A + BX [X = log(HBAC), Y = log(AKBR)] with high significance. This expression existed in both normal individuals and patients with liver, biliary tract or pancreas disease. The postoperative course was unsatisfactory because of liver dysfunction in cases whose value B was more than -0.6 in bisegmentectomy and more than -0.45 in uni- or subsegmentectomy. The coefficient B in the equation was suggested to contribute to the evaluation of hepatic functional reserve.
ISSN:0941-1291
DOI:10.1007/BF00308829