Calcium-loading test and bone disease in patients with urolithiasis

A group of 121 patients with a history of multiple or complicated calcium urolithiasis were divided into three subgroups: normal, absorptive and renal/resorptive calciuria by means of a calcium-loading test. Patients with renal hypercalciuria had lower bone mineral content (BMC) than the other group...

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Bibliographic Details
Published inProceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Vol. 20; p. 460
Main Authors Lindergård, B, Colleen, S, Månsson, W, Rademark, C, Rogland, B
Format Journal Article
LanguageEnglish
Published England 1983
Subjects
Adult
Bone and Bones - metabolism
Calcium - metabolism
Creatinine - urine
Female
Humans
Male
Middle Aged
Minerals - metabolism
Urinary Calculi - classification
Urinary Calculi - metabolism
Urinary Calculi - therapy
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Summary:A group of 121 patients with a history of multiple or complicated calcium urolithiasis were divided into three subgroups: normal, absorptive and renal/resorptive calciuria by means of a calcium-loading test. Patients with renal hypercalciuria had lower bone mineral content (BMC) than the other groups but did not differ in amount of bone or TmPO4/GFR. The 24-hour urine calcium excretion was elevated in patients with renal and absorptive type of hypercalciuria but not in patients with normal calcium-loading test and there was no correlation to BMC. The c-AMP/creatinine seemed to discriminate patients with resorptive calciuria from patients with renal calciuria. It is suggested that only patients with renal hypercalciuria should be treated with calcium-retaining drugs such as thiazides.
ISSN:0071-2736