Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity

Saved in:
Bibliographic Details
Published inTransplantation proceedings Vol. 26; no. 5; p. 2916
Main Authors Serino, F, Grevel, J, Napoli, K L, Kahan, B D, Strobel, H W
Format Journal Article
LanguageEnglish
Published United States 01.10.1994
Subjects
Aminopyrine - pharmacology
Animals
Chloramphenicol - pharmacology
Cyclosporine - toxicity
Cytochrome P-450 Enzyme System - biosynthesis
Cytochrome P-450 Enzyme System - metabolism
Enzyme Induction
Free Radical Scavengers - pharmacology
Ketoconazole - pharmacology
Kinetics
Lipid Peroxidation - drug effects
Male
Microsomes, Liver - drug effects
Microsomes, Liver - metabolism
NADP - metabolism
Phenobarbital - pharmacology
Proadifen - pharmacology
Rats
Rats, Sprague-Dawley
Online AccessGet more information

Cover

More Information
ISSN:0041-1345