Changing pattern of antimicrobial utilization in an Indian teaching hospital

A study was conducted at Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India, on the pattern of antimicrobial utilization in hospitalized patients. A retrospective study was conducted during a one-month period between January 18 to February 17, 1987. The data were...

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Bibliographic Details
Published inInternational journal of clinical pharmacology, therapy, and toxicology Vol. 28; no. 8; p. 339
Main Authors Pradhan, S C, Shewade, D G, Tekur, U, Zutshi, S, Pachiappan, D, Dey, A K, Adithan, C, Shashindran, C H, Bapna, J S
Format Journal Article
LanguageEnglish
Published Germany 01.08.1990
Subjects
Anti-Infective Agents - therapeutic use
Bacterial Infections - drug therapy
Bacterial Infections - prevention & control
Cross Infection - microbiology
Drug Resistance, Microbial
Drug Utilization
Hospitals, Teaching
Humans
India
India
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Summary:A study was conducted at Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India, on the pattern of antimicrobial utilization in hospitalized patients. A retrospective study was conducted during a one-month period between January 18 to February 17, 1987. The data were analyzed according to modified Kunin's criteria. The results were compared with a similar study conducted a decade ago. The study revealed a marked increase in the use of antimicrobial agents (from 19.9% to 56.1%). A more appropriate use of antimicrobial agents was observed (from 66.8% to 79.5%). A significant increase in their appropriate use for therapeutic purpose (50% to 88.2%), but not for prophylaxis (79.05% to 71.18%) was seen. The study revealed a marked increase in the use of antimicrobial agents during the last decade resulting in the emergence of nosocomial infections of resistant strains of organisms.
ISSN:0174-4879