Cefoperazone for urethritis due to penicillinase-producing Neisseria gonorrhoeae

Thirty-two men infected with penicillinase-producing Neisseria gonorrhoeae were treated with a single intramuscular dose of 0.5 gm of cefoperazone. Of the 29 patients who were followed up, only two (7%) failed to recover; seven patients (26%) had postgonococcal urethritis. The MICs of cefoperazone w...

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Bibliographic Details
Published inClinical therapeutics Vol. 6; no. 2; p. 193
Main Authors Kim, J H, Kim, Y T, Hwang, D H
Format Journal Article
LanguageEnglish
Published United States 1984
Subjects
Adult
Cefoperazone - therapeutic use
Gonorrhea - drug therapy
Humans
Male
Microbial Sensitivity Tests
Neisseria gonorrhoeae - drug effects
Urethritis - drug therapy
Urethritis - etiology
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Summary:Thirty-two men infected with penicillinase-producing Neisseria gonorrhoeae were treated with a single intramuscular dose of 0.5 gm of cefoperazone. Of the 29 patients who were followed up, only two (7%) failed to recover; seven patients (26%) had postgonococcal urethritis. The MICs of cefoperazone were 0.03 microgram/ml (three strains), 0.06 microgram/ml (11), 0.12 microgram/ml (nine), 0.25 microgram/ml (one), and 0.5 microgram/ml (one).
ISSN:0149-2918