Anemia and thrombocytopenia due to parvovirus B-19 infection in a pregnant woman

Anemia and thrombocytopenia in a patient with parvovirus B-19 and hepatitis C infection is reported. A seven month-pregnant 20 year-old patient had been first found to be anemic and thrombocytopenic 40 days before admission to our hospital and she had been given methylprednisolone and red cell trans...

Full description

Saved in:
Bibliographic Details
Published inJournal of medicine Vol. 28; no. 3-4; p. 245
Main Authors Timurağaoğlu, A, Sürücü, F, Nalçaci, M, Dinçol, G, Pekçelen, Y
Format Journal Article
LanguageEnglish
Published United States 1997
Subjects
Adult
Anemia - etiology
Female
Humans
Parvoviridae Infections - complications
Parvovirus B19, Human
Pregnancy
Pregnancy Complications
Thrombocytopenia - etiology
Online AccessGet more information

Cover

More Information
Summary:Anemia and thrombocytopenia in a patient with parvovirus B-19 and hepatitis C infection is reported. A seven month-pregnant 20 year-old patient had been first found to be anemic and thrombocytopenic 40 days before admission to our hospital and she had been given methylprednisolone and red cell transfusions. She gave birth to a healthy baby after only eight months of pregnancy. Ten days after delivery she was admitted to our hospital because of anemia and thrombocytopenia which did not respond to treatment. On admission, the blood count showed hemoglobin 8.1 g/dL, hematocrit 23.7%, white blood cells 11,200/microL, platelets 1000/microL, and reticulocytes 0.6%. Bone marrow smear and biopsy revealed erythroblastopenia and the absence of megakaryocytes. Liver enzymes were also high (alanine aminotransferase 1469 Units/L and aspartate aminotransferase 981 Units/L). In serologic studies PVB-19 IgM was found to be positive and hepatitis C virus RNA was detected. Red cell and platelet values returned to normal levels after cessation of methylprednisolone and concomitantly PVB-19 IgG was found positive in association with IgM in repeated determinations. PVB-19 was thought to be responsible for both anemia and thrombocytopenia.
ISSN:0025-7850