Variation in the protein coding region of the human p53 gene

This report describes a restriction fragment length polymorphism for the enzyme BglII caused by a conserved C to T change at residue 21 of the human p53 gene. This RFLP could potentially be misinterpreted as a rearrangement or a point mutation if paired constitutional tissue is not simultaneously an...

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Bibliographic Details
Published inOncogene Vol. 5; no. 9; p. 1409
Main Authors Ahuja, H G, Testa, M P, Cline, M J
Format Journal Article
LanguageEnglish
Published England 01.09.1990
Subjects
Aged
Humans
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Tumor Suppressor Protein p53 - genetics
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Summary:This report describes a restriction fragment length polymorphism for the enzyme BglII caused by a conserved C to T change at residue 21 of the human p53 gene. This RFLP could potentially be misinterpreted as a rearrangement or a point mutation if paired constitutional tissue is not simultaneously analyzed.
ISSN:0950-9232
1476-5594