Detection of antibody to LAV/HTLV-III in sera from hemophiliacs in China

Using ELISA, Western blots and immunofluorescence techniques, we identified seropositivity for lymphadenopathy-associated virus/human lymphotropic virus-III (LAV/HTLV-III) in 4 of 18 hemophiliacs and 1 AIDS patient. The four seropositive patients had received factor VIII prepared by Armour Company....

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Bibliographic Details
Published inAIDS research Vol. 2 Suppl 1; p. S147
Main Authors Zeng, Y, Fan, J, Zhang, Q, Wang, P C, Tang, D J, Zhon, S C, Zheng, X W, Liu, D P
Format Journal Article
LanguageEnglish
Published United States 01.12.1986
Subjects
Acquired Immunodeficiency Syndrome - complications
Acquired Immunodeficiency Syndrome - epidemiology
Antibodies, Viral - analysis
China
Enzyme-Linked Immunosorbent Assay
Factor VIII - therapeutic use
Fluorescent Antibody Technique
Hemophilia A - blood
Hemophilia A - complications
Hemophilia A - therapy
HIV - immunology
HIV Antibodies
Humans
Male
China
Measurement
Hemic System
Risk Factors
Viral Diseases
Commerce
Biology
Hiv Infections > transmission
Research Methodology
Diseases
Incidence
Economic Factors
Acquired Immunodeficiency Syndrome > transmission
Asia
China
Developing Countries
Physiology
Eastern Asia
Macroeconomic Factors
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Summary:Using ELISA, Western blots and immunofluorescence techniques, we identified seropositivity for lymphadenopathy-associated virus/human lymphotropic virus-III (LAV/HTLV-III) in 4 of 18 hemophiliacs and 1 AIDS patient. The four seropositive patients had received factor VIII prepared by Armour Company. The hemophiliacs are all asymptomatic. Given this documentation of introduction of LAV/HTLV-III into China, a national surveillance program is underway.
ISSN:0737-6006