Failure of pentagastrin to potentiate the effect of histamine

The gastric secretory response to pentagastrin and histamine administered jointly in maxiumum does by the subcutaneous route and in intravenous infusion, and in lower doses in infusion has been compared to the response to each of the two drugs administered by itself. No potentiating action was obser...

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Bibliographic Details
Published inActa medica Academiae Scientiarum Hungaricae Vol. 32; no. 2; p. 117
Main Author Kisfalvi, I
Format Journal Article
LanguageEnglish
Published Hungary 1975
Subjects
Drug Synergism
Gastric Mucosa - secretion
Histamine - administration & dosage
Histamine - pharmacology
Humans
Infusions, Parenteral
Injections, Subcutaneous
Male
Pentagastrin - administration & dosage
Pentagastrin - pharmacology
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Summary:The gastric secretory response to pentagastrin and histamine administered jointly in maxiumum does by the subcutaneous route and in intravenous infusion, and in lower doses in infusion has been compared to the response to each of the two drugs administered by itself. No potentiating action was observed, some additive action was found on infusion of the drugs and even this action was confined to the lowest dose-levels.
ISSN:0001-5989