Primary leiomyosarcoma of bone. An immunohistochemical and ultrastructural study

Primary leiomyosarcoma of bone is extremely rare. A 60-year-old woman had a mass in the right femur that was studied immunohistochemically and by electron microscopy. Human smooth-muscle actomyosin was detected in tumor cells, but human skeletal-muscle myoglobin and lysozyme (muramidase) were not. E...

Full description

Saved in:
Bibliographic Details
Published inArchives of pathology & laboratory medicine (1976) Vol. 107; no. 8; pp. 433 - 437
Main Authors Kawai, T, Suzuki, M, Mukai, M, Hiroshima, K, Shinmei, M
Format Journal Article
LanguageEnglish
Published United States 01.08.1983
Subjects
Actomyosin - analysis
Bone Neoplasms - ultrastructure
Female
Femoral Fractures - therapy
Hip Prosthesis
Histocytochemistry
Humans
Immunochemistry
Leiomyosarcoma - secondary
Leiomyosarcoma - ultrastructure
Middle Aged
Muramidase - analysis
Myoglobin - analysis
Urinary Bladder Neoplasms - secondary
Online AccessGet full text

Cover

More Information
Summary:Primary leiomyosarcoma of bone is extremely rare. A 60-year-old woman had a mass in the right femur that was studied immunohistochemically and by electron microscopy. Human smooth-muscle actomyosin was detected in tumor cells, but human skeletal-muscle myoglobin and lysozyme (muramidase) were not. Electron microscopy of the tumor showed findings suggestive of a smooth-muscle origin, such as myofilaments, dense bodies, pinocytotic vesicles, and basement membrane. The results were diagnostic of leiomyosarcoma rather than rhabdomyosarcoma, fibrosarcoma, or malignant fibrous histiocytoma, which are similar neoplasms. We believe that ours is the first case of primary leiomyosarcoma of the bone proved by immunohistochemistry.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0003-9985