Role of interferons in infectious diseases in the bovine species: effect on viruses and rickettsias

Successful protection was obtained with interferon treatment in experimental viral infections in the bovine species in a number of cases. The efficacy of the treatment against vaccinia virus infection and against rotavirus infection have been demonstrated. On the contrary, bovine herpes virus 1 (BHV...

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Bibliographic Details
Published inRevue d'élevage et de médecine vétérinaire des pays tropicaux Vol. 46; no. 1-2; p. 83
Main Authors Totté, P, De Gee, A L, Wérenne, J
Format Journal Article
LanguageEnglish
Published France 1993
Subjects
Animals
Anti-Infective Agents
Cattle
Cattle Diseases - microbiology
Cattle Diseases - prevention & control
Interferons - physiology
Rickettsiaceae Infections - prevention & control
Rickettsiaceae Infections - veterinary
Virus Diseases - prevention & control
Virus Diseases - veterinary
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Summary:Successful protection was obtained with interferon treatment in experimental viral infections in the bovine species in a number of cases. The efficacy of the treatment against vaccinia virus infection and against rotavirus infection have been demonstrated. On the contrary, bovine herpes virus 1 (BHV 1-causing rhinotracheitis and part of the shipping fever complex) infections were not inhibited by interferon (IFN). The authors have undertaken a study in cattle in Zimbabwe to assess the role of interferon in the resistance of the animals to Cowdria ruminantium. A good correlation between production of interferon by the animal following the infection, and the resistance of the animals against the rickettsia was demonstrated. This pointed out the possible "adjuvant" role of interferons and other cytokines.
ISSN:0035-1865