Surgical treatment of primary aldosteronism

An aldosterone-producing adenoma is the cause of primary aldosteronism in about 85%. Unilateral adrenalectomy cures the potassium wasting and normalizes the blood-pressure in more than 70%, independently of the severity or duration of the hypertension. The location of an aldosteronoma is best obtain...

Full description

Saved in:
Bibliographic Details
Published inAnnales chirurgiae et gynaecologiae Vol. 72; no. 3; p. 171
Main Authors Granberg, P O, Adamsson, U, Hamberger, B, Lins, P E
Format Journal Article
LanguageEnglish
Published Finland 1983
Subjects
Adenoma - diagnosis
Adenoma - surgery
Adrenal Cortex Diseases - pathology
Adrenal Cortex Diseases - surgery
Adrenal Cortex Neoplasms - diagnosis
Adrenal Cortex Neoplasms - surgery
Aldosterone - blood
Female
Humans
Hydrocortisone - blood
Hyperaldosteronism - surgery
Hyperplasia - pathology
Male
Tomography, X-Ray Computed
Online AccessGet more information

Cover

More Information
Summary:An aldosterone-producing adenoma is the cause of primary aldosteronism in about 85%. Unilateral adrenalectomy cures the potassium wasting and normalizes the blood-pressure in more than 70%, independently of the severity or duration of the hypertension. The location of an aldosteronoma is best obtained by computerized tomography and selective venous catheterization with determination of the aldosterone/cortisol ratio. When the biochemical studies suggest hyperplasia, medical treatment is recommended. It is, however, our policy to remove an adrenal gland with hyperplasia, when catheterization demonstrates unilateral hyperfunction. At operation a posterior or a flank approach is preferably used.
ISSN:0355-9521