Lichenoid eruption produced by captopril

Captopril, an oral active dipeptidylcarboxypeptidase inhibitor with antihypertensive properties, has been reported to have the following cutaneous side effects: macular and papular skin eruptions, urticaria, angioedema, mouth ulcers, pemphigus, and pityriasis rosea-like eruptions. Here, to the best...

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Bibliographic Details
Published inCutis (New York, N.Y.) Vol. 31; no. 1; p. 98
Main Authors Reinhardt, L A, Wilkin, J K, Kirkendall, W M
Format Journal Article
LanguageEnglish
Published United States 01.01.1983
Subjects
Captopril - adverse effects
Drug Eruptions - etiology
Humans
Lichen Planus - chemically induced
Male
Middle Aged
Pityriasis - chemically induced
Proline - analogs & derivatives
Sulfhydryl Compounds - metabolism
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Summary:Captopril, an oral active dipeptidylcarboxypeptidase inhibitor with antihypertensive properties, has been reported to have the following cutaneous side effects: macular and papular skin eruptions, urticaria, angioedema, mouth ulcers, pemphigus, and pityriasis rosea-like eruptions. Here, to the best of our knowledge, is the first case in which a pityriasis rosea-like eruption evolved into a lichenoid drug eruption. Also discussed is the remarkable similarity in the side effects of captopril, gold compounds, d-penicillamine, and organic mercurials.
ISSN:0011-4162