Multiple lymphangioendothelioma of the spleen in a 13-year-old girl

A 13-year-old girl had a history of an upper-quadrant abdominal mass for about six months. On exploratory laparotomy, multiple discrete large nodules were seen in the spleen. Histologically, the spleen had the unusual appearance of lymphangioma, in that there was a tremendous proliferatiion of endot...

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Bibliographic Details
Published inArchives of pathology (1960) Vol. 99; no. 11; p. 605
Main Authors Hamoudi, A B, Vassy, L E, Morse, T S
Format Journal Article
LanguageEnglish
Published United States 01.11.1975
Subjects
Adolescent
Female
Humans
Lymphangioma - pathology
Spleen - pathology
Splenic Neoplasms - pathology
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Summary:A 13-year-old girl had a history of an upper-quadrant abdominal mass for about six months. On exploratory laparotomy, multiple discrete large nodules were seen in the spleen. Histologically, the spleen had the unusual appearance of lymphangioma, in that there was a tremendous proliferatiion of endothelial cells that formed either papillary projections in the lumina of the cavernous lymphatic vessels or a solid mass of cells without the lumina. The changes were suggestive of sarcomatous transformation, but the evidence was not conclusive. A term "lymphangioendothelioma" is proposed for this multinodular tumor.
ISSN:0363-0153