Immunodeficiency syndrome associated with wasting and opportunistic infection in juvenile llamas: 12 cases (1988-1990)

Immunodeficiency was diagnosed as the cause of severe debilitating disease characterized by weight loss, failure to grow, and persistent infections that failed to respond to treatment in 12 young llamas. The llamas were affected after maternal-acquired immunity had decreased; failure of passive tran...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American Veterinary Medical Association Vol. 201; no. 7; p. 1070
Main Authors Hutchison, J M, Garry, F B, Johnson, L W, Quackenbush, S L, Getzy, D M, Jensen, W A, Hoover, E A
Format Journal Article
LanguageEnglish
Published United States 01.10.1992
Subjects
Animals
Camelids, New World
Female
Immunoglobulins - blood
Immunologic Deficiency Syndromes - complications
Immunologic Deficiency Syndromes - immunology
Immunologic Deficiency Syndromes - veterinary
Iron - blood
Lymphocyte Activation
Lymphoid Tissue - pathology
Male
Opportunistic Infections - complications
Opportunistic Infections - veterinary
Retrospective Studies
Weight Loss
Online AccessGet more information

Cover

More Information
Summary:Immunodeficiency was diagnosed as the cause of severe debilitating disease characterized by weight loss, failure to grow, and persistent infections that failed to respond to treatment in 12 young llamas. The llamas were affected after maternal-acquired immunity had decreased; failure of passive transfer of immunoglobulins thus was not suspected. Areas of lymph nodes containing T lymphocytes were hypocellular, suggesting T-cell involvement. High serum immunoglobulin concentrations were not found, despite the existence of infectious disease, suggesting at least secondary B-cell involvement. Results of lymphocyte blastogenesis assays were suggestive of B- and T-cell involvement. It was not possible to determine whether the condition was inherited or acquired.
ISSN:0003-1488
1943-569X